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Insulin Growth Factor 1 Receptor/PI3K/AKT Survival Pathway in Outer Segment Membranes of Rod Photoreceptors
PURPOSE: The authors previously reported that physiological light induces the tyrosine phosphorylation of insulin receptors (IRs), which leads to the activation of the phosphoinositide 3-kinase (PI3K) and Akt (serine/threonine protein kinase B) survival pathway in rod photoreceptor cells. Tissue-spe...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2670430/ https://ncbi.nlm.nih.gov/pubmed/18566464 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.08-2286 |
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