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Fenretinide-induced caspase-8 activation and apoptosis in an established model of metastatic neuroblastoma
BACKGROUND: Resistance of high-risk metastatic neuroblastoma (HR-NB) to high dose chemotherapy (HD-CT) raises a major therapeutic challenge in pediatric oncology. Patients are treated by maintenance CT. For some patients, an adjuvant retinoid therapy is proposed, such as the synthetic retinoid fenre...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2670318/ https://ncbi.nlm.nih.gov/pubmed/19331667 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-9-97 |
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