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RET oncogene in MEN2, MEN2B, MTC, and other forms of thyroid cancer: molecular genetics and therapeutic advances

Hereditary medullary thyroid carcinoma (MTC) is caused by specific autosomal dominant gain-of function mutations in the RET proto-oncogene. Genotype-phenotype correlations exist that help predict the presence of other associated endocrine neoplasms as well as the timing of thyroid cancer development...

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Detalhes bibliográficos
Main Authors: Lodish, Maya B., Stratakis, Constantine A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2670186/
https://ncbi.nlm.nih.gov/pubmed/18402529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1586/14737140.8.4.625
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