Streptococcus pneumoniae Endohexosaminidase D, Structural and Mechanistic Insight into Substrate-assisted Catalysis in Family 85 Glycoside Hydrolases

Endo-β-d-glucosaminidases from family 85 of glycoside hydrolases (GH85 endohexosaminidases) act to cleave the glycosidic linkage between the two N-acetylglucosamine units that make up the chitobiose core of N-glycans. Endohexosaminidase D (Endo-D), produced by Streptococcus pneumoniae, is believed t...

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Detalles Bibliográficos
Main Authors: Abbott, D. Wade, Macauley, Matthew S., Vocadlo, David J., Boraston, Alisdair B.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Enzyme Catalysis and Regulation
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2670171/
https://ncbi.nlm.nih.gov/pubmed/19181667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M809663200
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