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Polypurine Hairpins Directed against the Template Strand of DNA Knock Down the Expression of Mammalian Genes
We analyzed whether polypurine hairpins (PPRHs) had the ability to knock down gene expression. These hairpins are formed by two antiparallel purine domains linked by a loop that allows the formation of Hoogsteen bonds between both domains and Watson-Crick bonds with the target polypyrimidine sequenc...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2670163/ https://ncbi.nlm.nih.gov/pubmed/19261618 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M900981200 |
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