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Acetylation/Deacetylation Modulates the Stability of DNA Replication Licensing Factor Cdt1

Proper expression of the replication licensing factor Cdt1 is primarily regulated post-translationally by ubiquitylation and proteasome degradation. In a screen to identify novel non-histone targets of histone deacetylases (HDACs), we found Cdt1 as a binding partner for HDAC11. Cdt1 associates speci...

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Detalhes bibliográficos
Main Authors: Glozak, Michele A., Seto, Edward
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2670150/
https://ncbi.nlm.nih.gov/pubmed/19276081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M809394200
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