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Regulation of Neuronal Cell Death by MST1-FOXO1 Signaling

The protein kinase mammalian Sterile 20-like kinase 1 (MST1) plays a critical role in the regulation of cell death. Recent studies suggest that MST1 mediates oxidative stress-induced neuronal cell death by phosphorylating the transcription factor FOXO3 at serine 207, a site that is conserved in othe...

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Main Authors: Yuan, Zengqiang, Lehtinen, Maria K., Merlo, Paola, Villén, Judit, Gygi, Steven, Bonni, Azad
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2670133/
https://ncbi.nlm.nih.gov/pubmed/19221179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M900461200
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