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Rassf Family of Tumor Suppressor Polypeptides

The Rassf1–6 polypeptides each contain a Ras/Rap association domain, which enables binding to several GTP-charged Ras-like GTPases, at least in vitro or when overexpressed. The Ras/Rap association domains are followed by SARAH domains, which mediate Rassf heterodimerization with the Mst1/2 protein k...

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Detalhes bibliográficos
Main Authors: Avruch, Joseph, Xavier, Ramnik, Bardeesy, Nabeel, Zhang, Xian-feng, Praskova, Maria, Zhou, Dawang, Xia, Fan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2670104/
https://ncbi.nlm.nih.gov/pubmed/19091744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.R800073200
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