Proteasome-dependent degradation of the human estrogen receptor

In eukaryotic cells, the ubiquitin–proteasome pathway is the major mechanism for the targeted degradation of proteins with short half-lives. The covalent attachment of ubiquitin to lysine residues of targeted proteins is a signal for the recognition and rapid degradation by the proteasome, a large m...

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Main Authors: Nawaz, Zafar, Lonard, David M., Dennis, Andrew P., Smith, Carolyn L., O’Malley, Bert W.
Format: Artigo
Jezik:Inglês
Izdano: The National Academy of Sciences 1999
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC26701/
https://ncbi.nlm.nih.gov/pubmed/10051559
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