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Proteasome-dependent degradation of the human estrogen receptor

In eukaryotic cells, the ubiquitin–proteasome pathway is the major mechanism for the targeted degradation of proteins with short half-lives. The covalent attachment of ubiquitin to lysine residues of targeted proteins is a signal for the recognition and rapid degradation by the proteasome, a large m...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Nawaz, Zafar, Lonard, David M., Dennis, Andrew P., Smith, Carolyn L., O’Malley, Bert W.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1999
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC26701/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10051559/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.5.1858
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