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Only a Subset of Phosphoantigen-responsive γ(9)δ(2) T cells Mediate Protective TB Immunity

Mycobacterium tuberculosis and M. bovis-BCG induce potent expansions of human memory Vγ(9)(+)Vδ(2)(+) T cells capable of IFN-γ production, cytolytic activity and mycobacterial growth inhibition. Certain phosphoantigens expressed by mycobacteria can stimulate γ(9)δ(2) T cell expansions, suggesting th...

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Bibliografski detalji
Glavni autori: Spencer, Charles Thomas, Abate, Getahun, Blazevic, Azra, Hoft, Daniel F.
Format: Artigo
Jezik:Inglês
Izdano: 2008
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2670066/
https://ncbi.nlm.nih.gov/pubmed/18802050
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