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Calcium- and myosin-dependent changes in troponin structure during activation of heart muscle

Each heartbeat is triggered by a pulse of intracellular calcium ions which bind to troponin on the actin-containing thin filaments of heart muscle cells, initiating a change in filament structure that allows myosin to bind and generate force. We investigated the molecular mechanism of calcium regula...

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Bibliografische gegevens
Hoofdauteurs: Sun, Yin-Biao, Lou, Fang, Irving, Malcolm
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Blackwell Science Inc 2009
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2670030/
https://ncbi.nlm.nih.gov/pubmed/19015190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2008.164707
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