Epigenetic silencing of EphA1 expression in colorectal cancer is correlated with poor survival

Aberrant expression of Eph and ephrin proteins has well-established functions in oncogenesis and tumour progression. We describe EphA1 expression in 6 colorectal cancer (CRC) cell lines, 18 controls and 125 CRC specimens. In addition, a well-characterised cohort of 53 paired normal colon and CRCs wa...

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Autori principali: Herath, N I, Doecke, J, Spanevello, M D, Leggett, B A, Boyd, A W
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2009
Soggetti:
Molecular Diagnostics
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2670002/
https://ncbi.nlm.nih.gov/pubmed/19277044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6604970
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