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Hv1 proton channels are required for high-level NADPH oxidase-dependent superoxide production during the phagocyte respiratory burst
Granulocytes generate a “respiratory burst” of NADPH oxidase-dependent superoxide anion (O(2)(−∙)) production that is required for efficient clearance of bacterial pathogens. Hv1 mediates a voltage-gated H(+) channel activity that is proposed to serve a charge-balancing role in granulocytic phagocyt...
Gorde:
| Egile Nagusiak: | , , , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
National Academy of Sciences
2009
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2669790/ https://ncbi.nlm.nih.gov/pubmed/19372380 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0902761106 |
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