Fibroblast Growth Factor (FGF) and FGF Receptor-Mediated Autocrine Signaling in Non-Small-Cell Lung Cancer Cells

Despite widespread expression of epidermal growth factor (EGF) receptors (EGFRs) and EGF family ligands in non-small-cell lung cancer (NSCLC), EGFR-specific tyrosine kinase inhibitors (TKIs) such as gefitinib exhibit limited activity in this cancer. We propose that autocrine growth signaling pathway...

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Detalhes bibliográficos
Main Authors: Marek, Lindsay, Ware, Kathryn E., Fritzsche, Alexa, Hercule, Paula, Helton, Wallace R., Smith, Jennifer E., McDermott, Lee A., Coldren, Christopher D., Nemenoff, Raphael A., Merrick, Daniel T., Helfrich, Barbara A., Bunn, Paul A., Heasley, Lynn E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Pharmacology and Experimental Therapeutics 2009
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2669785/
https://ncbi.nlm.nih.gov/pubmed/18849352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.108.049544
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