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Loss of Modifier of Cell Adhesion Reveals a Pathway Leading to Axonal Degeneration
Axonal dysfunction is the major phenotypic change in many neurodegenerative diseases, but the processes underlying this impairment are not clear. Modifier of cell adhesion (MOCA) is a presenilin binding protein that functions as a guanine nucleotide exchange factor for Rac1. The loss of MOCA in mice...
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| Hlavní autoři: | , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Society for Neuroscience
2009
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2669744/ https://ncbi.nlm.nih.gov/pubmed/19129390 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3985-08.2009 |
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