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Deletion of TRPV1 Receptors Exaggerates Renal Damage in DOCA-Salt Hypertension

To determine whether the transient receptor potential vanilloid type 1 (TRPV1) channel provides protection against hypertension-induced renal damage, hypertension was induced by uninephrectomy and by giving deoxycorticosterone acetate (DOCA)-salt in wild type (WT) and TRPV1-null mutant (TRPV1(-/-))...

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Detalhes bibliográficos
Main Authors: Wang, Youping, Babánková, Dagmar, Huang, Jie, Swain, Greg M., Wang, Donna H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2669743/
https://ncbi.nlm.nih.gov/pubmed/18606907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.108.110197
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