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Apoptotic and Antiapoptotic Effects of CXCR4: Is It a Matter of Intrinsic Efficacy? Implications for HIV Neuropathogenesis

CXCR4, the specific receptor for the chemokine SDF-1α that also binds CXCR4-using HIV gp120s, affects survival of different cell types, including neurons. However, current data show that the outcome of CXCR4 activation on neuronal survival may vary depending on the ligand and/or the cellular conditi...

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Detalhes bibliográficos
Main Authors: KHAN, MUHAMMAD Z., BRANDIMARTI, RENATO, PATEL, JEEGAR P., HUYNH, NHA, WANG, JUN, HUANG, ZIWEI, FATATIS, ALESSANDRO, MEUCCI, OLIMPIA
Formato: Artigo
Idioma:Inglês
Publicado em: 2004
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2669736/
https://ncbi.nlm.nih.gov/pubmed/15585097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/aid.2004.20.1063
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