Apoptotic and Antiapoptotic Effects of CXCR4: Is It a Matter of Intrinsic Efficacy? Implications for HIV Neuropathogenesis

CXCR4, the specific receptor for the chemokine SDF-1α that also binds CXCR4-using HIV gp120s, affects survival of different cell types, including neurons. However, current data show that the outcome of CXCR4 activation on neuronal survival may vary depending on the ligand and/or the cellular conditi...

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Main Authors: KHAN, MUHAMMAD Z., BRANDIMARTI, RENATO, PATEL, JEEGAR P., HUYNH, NHA, WANG, JUN, HUANG, ZIWEI, FATATIS, ALESSANDRO, MEUCCI, OLIMPIA
Format: Artigo
Language:Inglês
Published: 2004
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2669736/
https://ncbi.nlm.nih.gov/pubmed/15585097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/aid.2004.20.1063
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