Evidence of ultraviolet type mutations in xeroderma pigmentosum melanomas

To look for a direct role of ultraviolet radiation (UV) exposure in cutaneous melanoma induction, we studied xeroderma pigmentosum (XP) patients who have defective DNA repair resulting in a 1000-fold increase in melanoma risk. These XP melanomas have the same anatomic distribution as melanomas in th...

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Bibliografiska uppgifter
Huvudupphovsmän: Wang, Yun, DiGiovanna, John J., Stern, Jere B., Hornyak, Thomas J., Raffeld, Mark, Khan, Sikandar G., Oh, Kyu-Seon, Hollander, M. Christine, Dennis, Philip A., Kraemer, Kenneth H.
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2009
Ämnen:
Biological Sciences
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2669353/
https://ncbi.nlm.nih.gov/pubmed/19329485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0812401106
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