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Mislocalized Scaffolding by the Na-H Exchanger NHE1 Dominantly Inhibits Fibronectin Production and TGF-β Activation

Secretion and assembly of the extracellular matrix protein fibronectin regulates a number of normal cell and tissue functions and is dysregulated in disease states such as fibrosis, diabetes, and cancer. We found that mislocalized scaffolding by the plasma membrane Na-H exchanger NHE1 suppresses fib...

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Bibliografiset tiedot
Päätekijät: Karydis, Anastasios, Jimenez-Vidal, Maite, Denker, Sheryl P., Barber, Diane L.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: The American Society for Cell Biology 2009
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2669038/
https://ncbi.nlm.nih.gov/pubmed/19225158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E08-08-0842
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