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Positive feedback between Cdc42 activity and H(+) efflux by the Na-H exchanger NHE1 for polarity of migrating cells

A fundamental feature of cell polarity in response to spatial cues is asymmetric amplification of molecules generated by positive feedback signaling. We report a positive feedback loop between the guanosine triphosphatase Cdc42, a central determinant in eukaryotic cell polarity, and H(+) efflux by N...

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Bibliografische gegevens
Hoofdauteurs: Frantz, Christian, Karydis, Anastasios, Nalbant, Perihan, Hahn, Klaus M., Barber, Diane L.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The Rockefeller University Press 2007
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2064788/
https://ncbi.nlm.nih.gov/pubmed/17984318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200704169
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