TCF7L2 Polymorphisms Modulate Proinsulin Levels and β-Cell Function in a British Europid Population

Rapidly accumulating evidence shows that common T-cell transcription factor (TCF)7L2 polymorphisms confer risk of type 2 diabetes through unknown mechanisms. We examined the association between four TCF7L2 single nucleotide polymorphisms (SNPs), including rs7903146, and measures of insulin sensitivi...

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Detalhes bibliográficos
Main Authors: Loos, Ruth J.F., Franks, Paul W., Francis, Richard W., Barroso, Inês, Gribble, Fiona M., Savage, David B., Ong, Ken K., O'Rahilly, Stephen, Wareham, Nicholas J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2668957/
https://ncbi.nlm.nih.gov/pubmed/17416797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db07-0055
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