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Induction of Immunologic Tolerance to Myelin Basic Protein Prevents Central Nervous System Autoimmunity and Improves Outcome After Stroke

BACKGROUND AND PURPOSE: Animals subjected to an inflammatory insult at the time of stroke are predisposed to the development of an inflammatory autoimmune response to brain. This response is associated with worse neurological outcome. Because induction of immunologic tolerance to brain antigens befo...

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Autori principali: Gee, J. Michael, Kalil, Angela, Thullbery, Matthew, Becker, Kyra J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2668930/
https://ncbi.nlm.nih.gov/pubmed/18323496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/STROKEAHA.107.501486
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