Immunologic tolerance to myelin basic protein decreases stroke size after transient focal cerebral ischemia

Immune mechanisms contribute to cerebral ischemic injury. Therapeutic immunosuppressive options are limited due to systemic side effects. We attempted to achieve immunosuppression in the brain through oral tolerance to myelin basic protein (MBP). Lewis rats were fed low-dose bovine MBP or ovalbumin...

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Detalhes bibliográficos
Main Authors: Becker, Kyra J., McCarron, Richard M., Ruetzler, Christl, Laban, Olgica, Sternberg, Esther, Flanders, Kathleen C., Hallenbeck, John M.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1997
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC23514/
https://ncbi.nlm.nih.gov/pubmed/9380727
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