A peptomimetic inhibitor of BCL6 with potent antilymphoma effects in vitro and in vivo

The BCL6 transcriptional repressor is the most commonly involved oncogene in diffuse large B-cell lymphomas (DLBCLs). BCL6 lymphomagenic activity is dependent on its ability to recruit corepressor proteins to a unique binding site on its N-terminal BTB domain. A recombinant peptide fragment of the S...

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Detalhes bibliográficos
Main Authors: Cerchietti, Leandro C., Yang, Shao Ning, Shaknovich, Rita, Hatzi, Katerina, Polo, Jose M., Chadburn, Amy, Dowdy, Steven F., Melnick, Ari
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2009
Assuntos:
Plenary Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2668844/
https://ncbi.nlm.nih.gov/pubmed/18927431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-07-168773
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