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A peptomimetic inhibitor of BCL6 with potent antilymphoma effects in vitro and in vivo
The BCL6 transcriptional repressor is the most commonly involved oncogene in diffuse large B-cell lymphomas (DLBCLs). BCL6 lymphomagenic activity is dependent on its ability to recruit corepressor proteins to a unique binding site on its N-terminal BTB domain. A recombinant peptide fragment of the S...
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| Hauptverfasser: | , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society of Hematology
2009
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2668844/ https://ncbi.nlm.nih.gov/pubmed/18927431 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-07-168773 |
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