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The Transcription Factor Snail Mediates Epithelial to Mesenchymal Transitions by Repression of Estrogen Receptor Alpha
The estrogen receptor-alpha (ER-α, ESR1) is a key regulatory molecule in mammary epithelial cell development. Loss of ER-α in breast cancer is correlated with poor prognosis, increased recurrence following treatment, and an elevated incidence of metastasis. A proposed molecular pathway by which ER-α...
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| Main Authors: | , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2007
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2668600/ https://ncbi.nlm.nih.gov/pubmed/17761946 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2007-0293 |
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