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The Transcription Factor Snail Mediates Epithelial to Mesenchymal Transitions by Repression of Estrogen Receptor Alpha

The estrogen receptor-alpha (ER-α, ESR1) is a key regulatory molecule in mammary epithelial cell development. Loss of ER-α in breast cancer is correlated with poor prognosis, increased recurrence following treatment, and an elevated incidence of metastasis. A proposed molecular pathway by which ER-α...

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Main Authors: Dhasarathy, Archana, Kajita, Masahiro, Wade, Paul A.
Format: Artigo
Jezik:Inglês
Izdano: 2007
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2668600/
https://ncbi.nlm.nih.gov/pubmed/17761946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2007-0293
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