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Identification of amino acid residues responsible for von Willebrand factor binding to sulfatide by charged-to-alanine-scanning mutagenesis

von Willebrand factor (VWF) performs its hemostatic functions through binding to various proteins. The A1 domain of VWF contains binding sites of not only physiologically important ligands, but also exogenous modulators that induce VWF-platelet aggregation. Sulfatides, 3-sulfated galactosyl ceramide...

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Detalhes bibliográficos
Main Authors: Nakayama, Takayuki, Matsushita, Tadashi, Yamamoto, Koji, Mutsuga, Noriko, Kojima, Tetsuhito, Katsumi, Akira, Nakao, Norihiko, Sadler, J. Evan, Naoe, Tomoki, Saito, Hidehiko
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Japan 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2668596/
https://ncbi.nlm.nih.gov/pubmed/18369690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12185-008-0065-8
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