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Intersubunit Interactions Modulate pH-Induced Activation of Membrane Fusion by the Junín Virus Envelope Glycoprotein GPC

The mature arenavirus envelope glycoprotein GPC is a tripartite complex comprising a stable signal peptide (SSP) in addition to the receptor-binding (G1) and transmembrane fusion (G2) subunits. We have shown previously that SSP is a key element in GPC-mediated membrane fusion, and that GPC sensitivi...

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Autori principali: York, Joanne, Nunberg, Jack H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2668491/
https://ncbi.nlm.nih.gov/pubmed/19224989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02410-08
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