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A Novel Zinc-Binding Domain Is Essential for Formation of the Functional Junín Virus Envelope Glycoprotein Complex

The envelope glycoprotein of the Junín arenavirus (GP-C) mediates entry into target cells through a pH-dependent membrane fusion mechanism. Unlike other class I viral fusion proteins, the mature GP-C complex retains a cleaved, 58-amino-acid signal peptide (SSP) as an essential subunit, required both...

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Hlavní autoři: York, Joanne, Nunberg, Jack H.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2007
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2168868/
https://ncbi.nlm.nih.gov/pubmed/17928348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01785-07
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