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Relaxed Selection and the Evolution of RNA Virus Mucin-Like Pathogenicity Factors

Mucin-like regions contribute to pathogenicity in a variety of negative-stranded RNA viruses. These regions are characterized by a preponderance of O-linked glycosylation. They evolve exceptionally rapidly yet maintain their function as pathogenicity factors. Two hypotheses have been proposed to exp...

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Autors principals: Wertheim, Joel O., Worobey, Michael
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2668480/
https://ncbi.nlm.nih.gov/pubmed/19224988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02358-08
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