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Phosphorylation by Cyclin C/Cyclin-Dependent Kinase 2 following Mitogenic Stimulation of Murine Fibroblasts Inhibits Transcriptional Activity of LSF during G(1) Progression

Transcription factor LSF is required for progression from quiescence through the cell cycle, regulating thymidylate synthase (Tyms) expression at the G(1)/S boundary. Given the constant level of LSF protein from G(0) through S, we investigated whether LSF is regulated by phosphorylation in G(1). In...

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Hlavní autoři: Saxena, Utsav H., Powell, Christina M. H., Fecko, Jill K., Cacioppo, Roxanne, Chou, Hubert S., Cooper, Geoffrey M., Hansen, Ulla
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2009
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2668376/
https://ncbi.nlm.nih.gov/pubmed/19237534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00687-08
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