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Design of (Gd-DO3A)(n)-Polydiamidopropanoyl-Peptide Nucleic Acid-d(Cys-Ser-Lys-Cys) Magnetic Resonance Contrast Agents
We hypothesized that chelating Gd(III) to 1,4,7-tris(carboxymethylaza)cyclododecane-10-azaacetylamide (DO3A) on peptide nucleic acid (PNA) hybridization probes would provide a magnetic resonance genetic imaging agent capable of hybridization to a specific mRNA. Because of the low sensitivity of Gd(I...
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Auteurs principaux: | , , , , , , , , , |
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Format: | Artigo |
Langue: | Inglês |
Publié: |
2008
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Sujets: | |
Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2668199/ https://ncbi.nlm.nih.gov/pubmed/18680101 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bip.21059 |
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