Parasite-Dependent Expansion of TNF Receptor II–Positive Regulatory T Cells with Enhanced Suppressive Activity in Adults with Severe Malaria

Severe Plasmodium falciparum malaria is a major cause of global mortality, yet the immunological factors underlying progression to severe disease remain unclear. CD4(+)CD25(+) regulatory T cells (Treg cells) are associated with impaired T cell control of Plasmodium spp infection. We investigated the...

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Hlavní autoři: Minigo, Gabriela, Woodberry, Tonia, Piera, Kim A., Salwati, Ervi, Tjitra, Emiliana, Kenangalem, Enny, Price, Ric N., Engwerda, Christian R., Anstey, Nicholas M., Plebanski, Magdalena
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2009
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2668192/
https://ncbi.nlm.nih.gov/pubmed/19390618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000402
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