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Accelerated Inactivation of the L-type Calcium Current Due to a Mutation in CACNB2b Underlies Brugada Syndrome
BACKGROUND: Recent studies have demonstrated an association between mutations in CACNA1c or CACNB2b and Brugada syndrome (BrS). Previously described mutations all caused a loss of function secondary to a reduction of peak calcium current (I(Ca)). We describe a novel CACNB2b mutation associated with...
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| Auteurs principaux: | , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2009
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2668128/ https://ncbi.nlm.nih.gov/pubmed/19358333 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2009.01.014 |
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