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Association Mapping and Significance Estimation via the Coalescent

The central questions asked in whole-genome association studies are how to locate associated regions in the genome and how to estimate the significance of these findings. Researchers usually do this by testing each SNP separately for association and then applying a suitable correction for multiple-h...

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Hlavní autoři: Kimmel, Gad, Karp, Richard M., Jordan, Michael I., Halperin, Eran
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2668060/
https://ncbi.nlm.nih.gov/pubmed/19026399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2008.10.017
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