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Genetic Defects in Surfactant Protein A2 Are Associated with Pulmonary Fibrosis and Lung Cancer
Idiopathic pulmonary fibrosis (IPF) is a lethal scarring lung disease that affects older adults. Heterozygous rare mutations in the genes encoding telomerase are found in ∼15% of familial cases. We have used linkage to map another disease-causing gene in a large family with IPF and adenocarcinoma of...
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Главные авторы: | , , , , , , , , , |
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Формат: | Artigo |
Язык: | Inglês |
Опубликовано: |
Elsevier
2009
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Предметы: | |
Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2668050/ https://ncbi.nlm.nih.gov/pubmed/19100526 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2008.11.010 |
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