Telomere Shortening in Familial and Sporadic Pulmonary Fibrosis

Rationale: Heterozygous mutations in the coding regions of the telomerase genes, TERT and TERC, have been found in familial and sporadic cases of idiopathic interstitial pneumonia. All affected patients with mutations have short telomeres. Objectives: To test whether telomere shortening is a frequen...

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Detalhes bibliográficos
Main Authors: Cronkhite, Jennifer T., Xing, Chao, Raghu, Ganesh, Chin, Kelly M., Torres, Fernando, Rosenblatt, Randall L., Garcia, Christine Kim
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2008
Assuntos:
E. Interstitial Lung Disease
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2556455/
https://ncbi.nlm.nih.gov/pubmed/18635888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.200804-550OC
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