Genotype-Imputation Accuracy across Worldwide Human Populations

A current approach to mapping complex-disease-susceptibility loci in genome-wide association (GWA) studies involves leveraging the information in a reference database of dense genotype data. By modeling the patterns of linkage disequilibrium in a reference panel, genotypes not directly measured in t...

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Bibliografiske detaljer
Main Authors: Huang, Lucy, Li, Yun, Singleton, Andrew B., Hardy, John A., Abecasis, Gonçalo, Rosenberg, Noah A., Scheet, Paul
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2009
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2668016/
https://ncbi.nlm.nih.gov/pubmed/19215730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2009.01.013
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