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Bisphosphonates: Mechanism of Action and Role in Clinical Practice

Bisphosphonates are primary agents in the current pharmacological arsenal against osteoclast-mediated bone loss due to osteoporosis, Paget disease of bone, malignancies metastatic to bone, multiple myeloma, and hypercalcemia of malignancy. In addition to currently approved uses, bisphosphonates are...

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Bibliographic Details
Main Authors: Drake, Matthew T., Clarke, Bart L., Khosla, Sundeep
Format: Artigo
Language:Inglês
Published: 2008
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2667901/
https://ncbi.nlm.nih.gov/pubmed/18775204
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