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Noncanonical Activation of Akt/Protein Kinase B in β-Cells by the Incretin Hormone Glucose-dependent Insulinotropic Polypeptide

Therapeutics based on the actions of the incretin hormones, glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP), have recently been introduced for the treatment of type 2 diabetes mellitus. The serine/threonine kinase Akt is a major mediator of incretin action on t...

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Detalhes bibliográficos
Main Authors: Widenmaier, Scott B., Sampaio, Arthur V., Underhill, T. Michael, McIntosh, Christopher H. S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2667764/
https://ncbi.nlm.nih.gov/pubmed/19233842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M809116200
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