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The Transcription of FOXO Genes Is Stimulated by FOXO3 and Repressed by Growth Factors

FOXO (Forkhead box O) transcription factors induce cell growth arrest and apoptosis, which can be prevented by FOXO phosphorylation by AKT in response to growth factors such as platelet-derived growth factors (PDGF) and insulin-like growth factor I (IGF-I). In addition to this well characterized pos...

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Detalhes bibliográficos
Main Authors: Essaghir, Ahmed, Dif, Nicolas, Marbehant, Catherine Y., Coffer, Paul J., Demoulin, Jean-Baptiste
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2667720/
https://ncbi.nlm.nih.gov/pubmed/19244250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M808848200
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