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The Transcription of FOXO Genes Is Stimulated by FOXO3 and Repressed by Growth Factors
FOXO (Forkhead box O) transcription factors induce cell growth arrest and apoptosis, which can be prevented by FOXO phosphorylation by AKT in response to growth factors such as platelet-derived growth factors (PDGF) and insulin-like growth factor I (IGF-I). In addition to this well characterized pos...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Biochemistry and Molecular Biology
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2667720/ https://ncbi.nlm.nih.gov/pubmed/19244250 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M808848200 |
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