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Disruption of the Blood–Brain Barrier Following ALA-Mediated Photodynamic Therapy

BACKGROUND AND OBJECTIVE: Photodynamic therapy (PDT) is a local antineoplastic treatment with the potential for tumor cell specificity. PDT using either hematoporphyrin derivatives or 5-aminolevulinic acid (ALA) has been reported to induce brain edema indicating disruption of the blood–brain barrier...

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Detalles Bibliográficos
Main Authors: Hirschberg, Henry, Uzal, Francisco A., Chighvinadze, David, Zhang, Michelle J., Peng, Qian, Madsen, Steen J.
Formato: Artigo
Idioma:Inglês
Publicado: 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2667623/
https://ncbi.nlm.nih.gov/pubmed/18798293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/lsm.20670
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