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TransCent: Computational enzyme design by transferring active sites and considering constraints relevant for catalysis

BACKGROUND: Computational enzyme design is far from being applicable for the general case. Due to computational complexity and limited knowledge of the structure-function interplay, heuristic methods have to be used. RESULTS: We have developed TransCent, a computational enzyme design method supporti...

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Detalhes bibliográficos
Main Authors: Fischer, André, Enkler, Nils, Neudert, Gerd, Bocola, Marco, Sterner, Reinhard, Merkl, Rainer
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2667513/
https://ncbi.nlm.nih.gov/pubmed/19208235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-10-54
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