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Impact of sample acquisition and linear amplification on gene expression profiling of lung adenocarcinoma: laser capture micro-dissection cell-sampling versus bulk tissue-sampling

BACKGROUND: The methods used for sample selection and processing can have a strong influence on the expression values obtained through microarray profiling. Laser capture microdissection (LCM) provides higher specificity in the selection of target cells compared to traditional bulk tissue selection...

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Библиографические подробности
Главные авторы: Klee, Eric W, Erdogan, Sibel, Tillmans, Lori, Kosari, Farhad, Sun, Zhifu, Wigle, Dennis A, Yang, Ping, Aubry, Marie C, Vasmatzis, George
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2009
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2667433/
https://ncbi.nlm.nih.gov/pubmed/19272143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1755-8794-2-13
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