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The Retinal Proteome in Experimental Diabetic Retinopathy: Up-regulation of Crystallins and Reversal by Systemic and Periocular Insulin

Diabetic retinopathy is the leading cause of blindness in working age persons. Targeted studies have uncovered several components of the pathophysiology of the disease without unveiling the basic mechanisms. This study describes the use of complementary proteomic and genomic discovery methods that r...

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Autori principali: Fort, Patrice E., Freeman, Willard M., Losiewicz, Mandy K., Singh, Ravi S. J., Gardner, Thomas W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2667355/
https://ncbi.nlm.nih.gov/pubmed/19049959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M800326-MCP200
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