A Large Number of Protein Expression Changes Occur Early in Life and Precede Phenotype Onset in a Mouse Model for Huntington Disease

Huntington disease (HD) is fatal in humans within 15–20 years of symptomatic disease. Although late stage HD has been studied extensively, protein expression changes that occur at the early stages of disease and during disease progression have not been reported. In this study, we used a large two-di...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Zabel, Claus, Mao, Lei, Woodman, Ben, Rohe, Michael, Wacker, Maik A., Kläre, Yvonne, Koppelstätter, Andrea, Nebrich, Grit, Klein, Oliver, Grams, Susanne, Strand, Andrew, Luthi-Carter, Ruth, Hartl, Daniela, Klose, Joachim, Bates, Gillian P.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: American Society for Biochemistry and Molecular Biology 2009
Θέματα:
Research
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2667354/
https://ncbi.nlm.nih.gov/pubmed/19043139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M800277-MCP200
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