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Role of the A chain in thrombin function
The A chain of thrombin is covalently linked to the catalytic B chain but is separate from any known epitope for substrate recognition. In this study we present the results of the Ala replacement of 12 charged residues controlling the stability of the A chain and its interaction with the B chain. Re...
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| Main Authors: | , , |
|---|---|
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2008
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2667268/ https://ncbi.nlm.nih.gov/pubmed/18470478 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-008-8179-y |
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