Sperm-derived SPANX-B is a clinically relevant tumor antigen that is expressed in human tumors and readily recognized by human CD4(+) and CD8(+) T cells

PURPOSE: The sperm-derived SPANX family proteins can be found expressed in human tumors. Here, we aimed to perform a comprehensive study to evaluate immunotherapeutic relevance of one of its members, SPANX-B. We wanted to test its expression pattern in human tumors; and to evaluate CD4(+) and CD8(+)...

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Detalhes bibliográficos
Main Authors: Almanzar, Giovanni, Olkhanud, Purevdorj B., Bodogai, Monica, Dell’Agnola, Chiara, Baatar, Dolgor, Hewitt, Stephen M., Ghimenton, Claudio, Tummala, Mohan K., Weeraratna, Ashani T., Hoek, Keith Sean, Kouprina, Natalay, Larionov, Vladimir, Biragyn, Arya
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2667247/
https://ncbi.nlm.nih.gov/pubmed/19276289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-08-1290
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